Moriarity Publications

Selected Publications

  • Kurata M, Wolf NK, Lahr WS, Weg MT, Kluesner MG, Lee S, Hui K, Shiraiwa M, Webber BR, Moriarity BS. Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays. PLoS One. 2018 Sep 17; 13(9):e0198714. PMCID: PMC6141065
  • Shapovalova M, Pyper SR, Moriarity BS, LeBeau AM. The Molecular Imaging of Natural Killer Cells. Mol Imaging. 2018 Jan-Dec; 17: 1536012118794816. PMCID: PMC6134484
  • Johnson MJ, Laoharawee K, Lahr WS, Webber BR, Moriarity BS. Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease. Sci Rep. 2018 Aug 14: 8(1): 12144. PMCID: PMC6092381
  • Li Y, Hermanson DL, Moriarity BS, Kaufman DS. Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity.  Cell Stem Cell. 2018 Aug 2; 23(2): 181-192. 
  • Kurata M, Yamamoto K, Moriarity BS, Kitagawa M, Largaespada DA. CRISPR/Cas9 library screening for drug target discovery. J Hum Genet. 2018 Feb; 63(2):179-186. 
  • Scott MC, Temiz NA, Sarver AE, LaRue RS, Rathe SK, Varshney J, Wolf NK, Moriarity BS, O'Brien TD, Spector LG, Largaespada DA, Modiano JF, Subramanian S, Sarver AL. Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma. Cancer Res. 2018 Jan 15; 78(2): 326-337. PMCID: PMC5935134
  • Webber BR, O'Connor KT, McElmurry RT, Durgin EN, Eide CR, Lees CJ, Riddle MJ, Mathews WE, Frank NY, Kluth MA, Ganss C, Moriarity BS, Frank MH, Osborn MJ, Tolar J. Rapid generation of Col7a1-/- mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells. Lab Invest. 2017 Oct; 97(10): 1218-1224. PMCID: PMC5623156
  • Chaudhary R, Gryder B, Woods WS, Subramanian M, Jones MF, Li XL, Jenkins LM, Shabalina SA, Mo M, Dasso M, Yang Y, Wakefield LM, Zhu Y, Frier SM, Moriarity BS, Prasanth KV, Perez-Pinera P, Lal A. Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3. Elife. 2017 Jun 5; 6. PMCID: PMC5470874
  • Dorr CR, Remmel RP, Muthusamy A, Fisher J, Moriarity BS, Yasuda K, Wu B, Guan W, Schuetz EG, Oetting WS, Jacobson PA, Israni AK. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism. Drug Metab Dispos. 2017 Aug; 45(8): 957-965. PMCID: PMC5518718
  • Patrinostro X, O'Rourke AR, Chamberlain CM, Moriarity BS, Perrin BJ, Ervasti JM. Relative importance of bcyto- and ycyto-actin in primary mouse embryonic fibroblasts. Mol Biol Cell. 2017 Mar 15; 28(6): 771-782. PMCID: PMC5349784
  • Pomeroy EJ, Lee LA, Lee RDW, Schirm DK, Temiz NA, Ma J, Gruber TA, Diaz-Flores E, Moriarity BS, Downing JR, Shannon KM, Largaespada DA, Eckfeldt CE. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia. Oncogene. 2017 Jun 8; 36(23): 3263-3273. PMCID: PMC5464975
  • Marko TA, Shamsan GA, Edwards EN, Hazelton PE, Rathe SK, Cornax I, Overn pR, Varshney J, Diessner BJ, Moriarity BS, O'Sullivan MG, Odde DJ, Largaespada DA. Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma. Sci Rep. 2016 Dec 14; 6: 39059. PMCID: PMC5155223
  • Kurata M, Rathe SK, Bailey NJ, Aumann NK, Jones JM, Veldhuijzen GW, Moriarity BS, Largaespada DA. Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML. Sci Rep. 2016 Nov 3; 6: 36199. PMCID: PMC5093682
  • Eckfeldt CE, Pomeroy EJ, Lee RD, Hazen KS, Lee LA, Moriarity BS, Largaespada DA. RALB provides critical survival signals downstream of Ras in acute myeloid leukemia. Oncotarget. 2016 Oct 4; 7(40): 65147-65156. PMCID: PMC5323144
  • Yun YS, Kim KH, Tschida B, Sachs Z, Noble-Orcutt KE, Moriarity BS, Ai T, Ding R, Williams J, Chen L, Largaespada D, Kim DH. mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress. Mol Cell. 2016 Feb 18; 61(4): 625-639. PMCID: PMC4870089

For a comprehensive list of recent publications, refer to PubMed, a service provided by the National Library of Medicine.