Pediatric Bone Health Program

Comprehensive Pediatric Bone Health Program

The Comprehensive Pediatric Bone Health Program at the University of Minnesota comprises a team of specialists committed to the care of children with bone diseases. Our team includes physicians representing the fields of endocrinology, genetics, sports medicine, genetic counselors, dieticians, and care coordinators. Our goal is to provide comprehensive patient and family-focused care and offer access to the latest research studies. The program serves as an outpatient referral center for the prevention, diagnosis and treatment of bone diseases in children:

Boy giving thumbs up

  • Calcium abnormalities (hypocalcemia, hypercalcemia, DiGeorge syndrome)
  • Fibrous dysplasia
  • Fractures
  • Hypophosphatemia
  • Low bone density
  • Osteogenesis imperfecta
  • Osteopetrosis
  • Osteoporosis
  • Parathyroid gland disorders (hypoparathyroidism, pseudohypoparathyroidism, hyperparathyroidism)
  • Rickets
  • Vitamin D deficiency or resistance
  • Secondary conditions predisposing to low bone mineral density:
    • Bone marrow transplantation
    • Childhood cancer treatment
    • Neuromuscular diseases, including muscular dystrophy
    • Rheumatologic diseases
    • Long-term use of glucocorticoids

We recognize that childhood and adolescence are critical periods for bone mineralization and that early interventions are important to attain adequate bone density and mobility, and to prevent fractures. Evaluation may include blood and urine tests, genetic testing, including next generation sequencing, comparative genomic hybridization (CGH) and others, bone x-rays, and dual-energy x-ray absorptiometry (DXA) to measure bone mineral density. Treatment options may include dietary intervention, calcium and vitamin D supplementation, infusion of pamidronate or other bisphophonates, physical therapy, and orthopedic surgery. We also offer participation in research studies.