Margaret MacMillan, MD

Professor, Department of Pediatrics

Margaret MacMillan

Contact Info

macmi002@umn.edu

Office Phone 612-626-2961

Fax 612-626-4074

Office Address:
Pediatric BMT
D578 Mayo
420 Delaware St SE
Minneapolis, MN 55455

Mailing Address:
Pediatric BMT
MMC 484 Mayo
8484B (Campus Delivery Code)
420 Delaware St SE
Minneapolis, MN 55455

Professor, Department of Pediatrics

Faculty Member, Pediatric Blood and Marrow Transplant (BMT) Center


Pediatric Hematologist Oncologist


MD, University of Toronto Medical School, Ontario, Canada

Residency in Pediatrics, The Hospital for Sick Children, University of Toronto, Ontario, Canada

Fellowship in Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada

Fellowship in Blood and Marrow Transplantation, University of Minnesota Medical School, Minneapolis, MN

MS, Nutritional Sciences, University of Toronto, Ontario, Canada

Summary

Dr. MacMillan is a Professor of Pediatrics in the Division of Blood and Marrow Transplantation and attends on the Pediatric Blood and Marrow Transplantation service. Dr. MacMillan is the Clinical Medical Director of the Pediatric BMT Program and the Medical Director of the Unrelated Donor Program at the University of Minnesota. Dr. MacMillan received her MSc degree at the University of Toronto in 1989 and her M.D. degree at the University of Toronto in 1991. She completed her internship residency in Pediatrics, and post-doctoral fellowship in Hematology-Oncology at the University of Toronto School of Medicine in 1997. She then completed a Blood and Marrow Transplant fellowship at the University of Minnesota in 1999 after which she joined the faculty. Dr. MacMillan's research is focused on the development and implementation of novel strategies for preventing the immunologic complications of allogeneic hematopoietic stem cell transplantation. She is the Principal Investigator of 10 phase I/II clinical trials at the University of Minnesota. In collaboration with Bruce Blazar, M.D., she is studying the safety and efficacy of T regulatory cells to prevent graft-versus-host disease. Dr. MacMillan is co-director with John Wagner, M.D. of the University of Minnesota Fanconi Anemia Comprehensive Care Clinic, which follows the largest number of Fanconi anemia patients in the world. Dr. MacMillan has authored more than 30 articles and book chapters on the subject of hematopoietic stem cell transplantation, and is a member of numerous professional societies. She is board certified in Pediatrics.

Awards & Recognition

  • Irvine McQuarrie Research Scholar, University of Minnesota (2000)
  • Cooley's Anemia Fellowship, Boston, Massachusetts (1997)
  • Schilling Scholarship Award in Pediatrics, University of Toronto (1991)
  • Charles E. Snelling Scholarship in Pediatrics, University of Toronto (1990)
  • Life Sciences Graduate Degree Completion Award, University of Toronto (1988)
  • Open Scholarship, University of Toronto (1987)
  • Ontario Graduate Scholarship (1986)

Research

Research Summary/Interests

  1. Acute Graft-Versus-Host Disease
    • T regulatory cells to prevent GVHD
    • Novel pharmacologic agents/ regimens
  2. Fanconi anemia
    • Novel preparative therapies
    • Gene therapy - multipotent adult stem cell
    • Mechanisms to speed immune recovery and reduce infection after transplantation
  3. Juvenile Myelomonocytic Leukemia
    • Novel phase I agents
    • Novel preparative therapies

Clinical

Specialties

  • Blood and marrow transplantation, Fanconi&rsquo
  • s anemia, Juvenile myelomonocytic leukemia

Board Certifications

Pediatrics